Expression of macrophage inducible proteins (mips) in yeast...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/19 (2006.01) A61K 38/19 (2006.01) C07K 14/52 (2006.01) C07K 19/00 (2006.01) C12N 1/19 (2006.01) C12N 15/62 (2006.01)

Patent

CA 2091266

2091266 9205198 PCTABS00011 Methods for the expression of mammalian MIP-1.alpha. and MIP-1.beta. are disclosed. The methods generally comprise introducing into a yeast cell, a DNA molecule capable of directing the expression and if desired the secretion of either MIP-1.alpha. or MIP-1.beta.. Methods for expression of constructs encoding both MIP-1.alpha. and MIP-1.beta. are also described. The MIP molecules so produced are biologically active.

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