Expression profiles for breast cancer and methods of use

Details Expression profiles for breast cancer and methods of use Expression profiles for breast cancer and methods of use

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01) G01N 33/50 (2006.01)

Patent

CA 2516182

The present invention relates to gene expression profiles for breast cancer, microarrays comprising nucleic acid sequences representing gene expression profiles, and methods of using expression profiles and microarrays. The invention also provides methods and compositions for diagnostic assays for detecting cancer and therapeutic methods and compositions for treating cancer. The invention also provides methods for designing, identifying, and optimizing therapeutics for cancer.

La présente invention concerne des profiles d'expression génique pour le cancer du sein, des plaques de micro-titration comprenant des séquences d'acides nucléiques qui représentent des profils d'expression génique, ainsi que des méthodes d'utilisation de ces profils d'expression et plaques de micro-titration. L'invention concerne également des méthodes et des compositions pour essais diagnostiques aux fins de détection du cancer ainsi que des méthodes et des compositions pour le traitement du cancer. Sont également décrites des méthodes de conception, d'identification et d'optimisation de méthodes thérapeutiques pour le cancer.

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