Expression profiling platform technology

Details Expression profiling platform technology Expression profiling platform technology

G - Physics

01

N

G01N 33/68 (2006.01)

Patent

CA 2584223

The present invention relates to an efficient mAb panel-based expression profiling technology platform suitable for global and accurate measurement of proteins, peptides and metabolites in complex mixtures. The platform is comprised of new and well established technologies that are coupled in a unique fashion to provide a novelplatform technology for(i) the discovery of differentially displayed elements of complex protein, peptide and metabolite mixtures and (ii) the development of robust mAb based assays that detect the differentially expressed elements.

L'invention concerne une plate-forme utilisée dans la technologie de profilage d'expression sur la base d'un panneau mAb efficace permettant la mesure totale et précise de protéines, de peptides et de métabolites dans des mélanges complexes. La plate-forme comprend de nouvelles technologies ainsi que des technologies bien établies qui sont associées, de façon à produire une nouvelle technologie de plates-formes permettant (i) la découverte d'éléments affichés différemment de mélanges complexes de protéines, de peptides et de métabolites, et (ii) le développement d'essais biologiques robustes à base de mAb qui détectent les éléments exprimés différemment.

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