Expression vector for phytolacca antiviral protein

Details Expression vector for phytolacca antiviral protein Expression vector for phytolacca antiviral protein

C - Chemistry, Metallurgy

12

N

C12N 15/29 (2006.01) A61K 47/48 (2006.01) C07K 14/415 (2006.01) C12N 1/21 (2006.01) C12N 9/24 (2006.01) C12N 15/56 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2102859

The present invention provides a novel expression vector for Phytolacca antiviral protein isolated from Phytolacca americana L. and a microorganism transformed with said PAP expression vector. In accordance with the present invention, biologically active PAP can be produced in a massive manner from the microorganism transformed with the expression vector of the invention; and, therefore, the recombinant PAP can be practically applied to various fields, e.g., the molecular studies on PAP and treatment of AIDS employing immunoconjugate.

L'invention porte sur un nouveau vecteur d'expression pour la protéine antivirale de Phytolacca, isolée à partir de Phytolacca americana L., et sur un microorganisme transformé avec ce vecteur d'expresson de la PAP. Selon la présente invention, la PAP peut être produite massivement à partir du microorganisme transformé avec le vecteur d'expression de l'invention; la PAP recombinante peut donc être appliquée à divers domaines pratiques, comme les études moléculaires sur la PAP et le traitement du SIDA faisant appel aux immunoconjugués.

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