Expression vectors and their use in the preparation of...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/85 (2006.01) A61K 31/70 (2006.01) A61K 48/00 (2006.01) C07K 14/16 (2006.01) C12N 5/10 (2006.01) C12N 15/12 (2006.01) C12N 15/33 (2006.01) C12N 15/49 (2006.01)

Patent

CA 2083812

Expression vectors and their use in the preparation of HIV-resistant human cells for therapeutic applications Abstract The present invention relates to the targeted blocking of the genetic information of the viral messenger ribo- nucleic acid (mRNA) for virus replication (e.g. of HIV) in transfected, haematopoietic cells with particularly suitable expression systems, which express a comple- mentary "antisense RNA".

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