Expression vectors for treating bacterial infections

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/74 (2006.01) A23K 1/17 (2006.01) A61K 35/74 (2006.01) A61K 38/16 (2006.01) A61K 48/00 (2006.01) A61P 31/04 (2006.01) C07K 14/245 (2006.01) C12N 1/21 (2006.01) C12N 15/31 (2006.01) C12N 15/63 (2006.01) C12P 21/02 (2006.01)

Patent

CA 2592344

The present invention is compositions and methods for producing anti-bacterial polypeptides, and for using those compositions and methods for treating diseases and conditions caused by a bacterial infection. More specifically, the compositions and methods include treating a gram-negative bacterium with a gram-positive host that produces a polypeptide effective against the gram-negative bacterium.

La présente invention concerne des préparations et des méthodes pour la synthèse de polypeptides antibactériens, ainsi que l'utilisation de ces préparations et méthodes dans le traitement de maladies et d'états pathologiques causés par une infection bactérienne. Plus spécifiquement, lesdites préparations et méthodes incluent le traitement d'une bactérie Gram-négative à l'aide d'un hôte Gram-positif produisant un polypeptide actif contre ladite bactérie Gram-négative.

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