C - Chemistry – Metallurgy – 08 – G
Patent
C - Chemistry, Metallurgy
08
G
C08G 69/10 (2006.01) A61K 47/42 (2006.01) A61K 47/48 (2006.01) C07K 1/00 (2006.01) C07K 7/08 (2006.01) C07K 14/00 (2006.01) C07K 19/00 (2006.01) C12N 15/00 (2006.01)
Patent
CA 2748314
The present invention relates to compositions comprising biologically active proteins linked to extended recombinant polypeptide (XTEN), isolated nucleic acids encoding the compositions and vectors and host cells containing the same, and methods of using such compositions in treatment of glucose- related diseases, metabolic diseases, coagulation disorders, and growth hormone-related disorders and conditions.
La présente invention concerne des compositions comprenant des protéines biologiquement actives liées à un polypeptide recombinant étendu (XTEN), des acides nucléiques isolés codant pour les compositions ainsi que des vecteurs et des cellules hôtes les contenant, et des procédés d'utilisation de ces compositions dans le traitement de maladies liées au glucose, de maladies métaboliques, de troubles de la coagulation, et de troubles et de conditions liés aux hormones de croissance.
Cleland Jeffrey L.
Geething Nathan
Schellenberger Volker
Silverman Joshua
Spink Benjamin
Amunix Operating Inc.
Gowling Lafleur Henderson Llp
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