Extended transdermal contraceptive regimens

A - Human Necessities – 61 – K

Patent

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Details

A61K 9/70 (2006.01) A61K 31/567 (2006.01) A61K 31/57 (2006.01) A61P 15/18 (2006.01)

Patent

CA 2517778

A method of contraception is described comprising the step of administering to a menstruating female a cycle of contraceptive therapy, said cycle of therapy including, for at least 42 successive days, the administration of a combination of an estrogen and a progestogen in a contraceptively effective daily dosage wherein said progestogen is a potent sulfatase inhibiting progestogen and said cycle of therapy including 4-8 days which are free of estrogen administration following said at least 42 successive days. A method of contraception is also described which provides enhanced bleeding control and enchanced continuation and satisfaction rates in menstruating females using the method.

L'invention concerne une méthode de contraception comprenant une étape consistant à soumettre une femme menstruée à un cycle de traitement contraceptif, ledit cycle consistant à administrer, pendant au moins 42 jours consécutifs, une combinaison d'un oestrogène et d'un progestogène, à raison d'une dose quotidienne efficace sur le plan contraceptif, ledit progestogène étant un progestogène constituant un puissant inhibiteur de la sulfatase. Ledit cycle comprenant une période de 4 à 8 jours sans administration d'oestrogène, faisant suite auxdits 42 jours successifs. L'invention concerne également une méthode de contraception qui permet d'obtenir une meilleure régulation des menstruations ainsi que de meilleurs taux de satisfaction et de continuité d'utilisation chez les femmes menstruées faisant appel à cette méthode.

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