A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/70 (2006.01) A61K 31/245 (2006.01)
Patent
CA 2588732
The present invention provides to patches having excellent skin-permeability and therapeutic effect by the drug with lower irritation. In an external patch in which an adhesive layer containing an adhesive base and a drug are laminated with a backing, the external patch wherein the adhesive base contains 5-50 % by weight of synthetic rubber polymer, 10-60 % by weight of adhesive resin and 25-60 % by weight of liquid paraffin, and the drug is etofenamate. According to the present invention, there is obtainable the patches having excellent skin-permeability and therapeutic effect by the drug with lower irritation.
La présente invention concerne des dispositifs transdermiques offrant une excellente perméabilité cutanée et un excellent effet thérapeutique induit par le médicament, associés à un faible degré d~irritation. L~invention décrit un dispositif transdermique externe dans lequel une couche adhésive contenant une base adhésive et un médicament est laminée au moyen d~un support; le dispositif transdermique externe contenant la base adhésive comprend 5-50 % en poids de polymère de caoutchouc synthétique, 10-60 % en poids de résine adhésive et 25-60 % en poids de paraffine liquide; le médicament de l'invention est l'étofénamate. La présente invention permet d~obtenir des dispositifs transdermiques offrant une excellente perméabilité cutanée et un excellent effet thérapeutique induit par le médicament, associés à un faible degré d~irritation.
Ishima Tomohiro
Yamaji Masahiro
Yamasaki Hiroyuki
Drossapharm Ag
Kirby Eades Gale Baker
Teikoku Seiyaku Co. Ltd.
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