A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 47/32 (2006.01) A61K 9/70 (2006.01) A61K 31/192 (2006.01) A61L 15/24 (2006.01) A61L 15/44 (2006.01) A61L 15/58 (2006.01) A61K 47/44 (2006.01)
Patent
CA 2599334
An external plaster inducing percutaneous absorption, comprising a support and, superimposed thereon, a pressure sensitive adhesive layer, wherein the pressure sensitive adhesive layer contains as essential components a styrene- isoprene-styrene block copolymer (SIS), a tackifying resin and a softening agent, to which flurbiprofen is added as an active ingredient. This external plaster containing flurbiprofen realizes stable release of contained flurbiprofen external plaster over a prolonged period of time and excels in pharmaceutical preparation stability, thereby exhibiting strikingly enhanced drug release performance.
La présente invention concerne un emplâtre externe induisant une absorption percutanée, comprenant un support et, superposée sur ce dernier, une couche adhésive sensible à la pression, qui contient, en tant que composants principaux, un copolymère séquencé styrène-isoprène-styrène (SIS), une résine d~adhérence et un agent de dérésinage, auxquels on ajoute du flurbiprofène en tant que principe actif. Cet emplâtre externe contenant du flurbiprofène assure une libération stable du flurbiprofène pendant une période de temps prolongée ; il possède d~excellentes propriétés sur le plan de la stabilité de la préparation pharmaceutique, ce qui permet d~assurer une libération médicamenteuse extrêmement améliorée.
Sugawara Takaya
Yamaji Masahiro
Smart & Biggar
Teikoku Seiyaku Co. Ltd.
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