External preparation for skin containing flavanone derivative

A - Human Necessities – 61 – K

Patent

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Details

A61K 8/49 (2006.01) A61K 31/353 (2006.01) A61P 17/16 (2006.01) A61Q 19/08 (2006.01) C12Q 1/02 (2006.01)

Patent

CA 2642524

To increase a tissue regeneration ability of a living body such as a collagen production ability of fibroblast in the dermis in a skin defect area typified by a large wrinkle or wound, a flavanone derivative such as farrerol is used as an active ingredient of an external preparation for skin. Further, to efficiently screen a substance having an excellent effect on promoting wound healing, the remodeling action of collagen fiber bundle is tested by using a skin wound model.

La présente invention concerne la capacité de régénération des tissus d'un corps vivant telle que la capacité de production de collagène de fibroblaste dand le derme dans une région de la peau qui présente un défaut, typifiée par une grande ride ou cicatrice, un dérivé de flavanone tel que du farrérol est utilisé comme ingrédient actif d'une préparation externe pour la peau. En outre, pour dépister de manière efficace une substance ayant un effet excellent sur la promotion de guérison de la cicatrice, l'action de remodelage d'un faisceau de fibres de collagènes est testé en utilisant un modèle de cicatrice de la peau.

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