Extracellular matrix cancer vaccine adjuvant

C - Chemistry – Metallurgy – 12 – N

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C12N 5/071 (2010.01) A61K 39/00 (2006.01) A61P 35/00 (2006.01) A61P 37/04 (2006.01) C07K 14/78 (2006.01)

Patent

CA 2667075

Compositions suitable for use as adjuvants in the preparation of vaccines, particularly those vaccines useful in the treatment of cancer, are provided. Methods for inhibiting tumor growth in an animal are also disclosed. Methods for immunizing an animal against cancer, such as prostate cancer, are also described. The adjuvants described are comprised of an extracellular matrix material, such as small intestinal submucosal (SIS) tissue. The preparations may take the form of sheets, gels, liquids (injectable), trocar, or other solid or semi-solid preparation. The invention provides for enhanced tumor inhibition of 2-fold or greater, compared to vaccine preparations without the extracellular matrix material, or from 4- to 5-fold, compared to preparations without the adjuvant promoting extracellular materials.

L'invention concerne des compositions convenant pour être utilisées en tant qu'adjuvants dans la préparation de vaccins, en particulier dans la préparation des vaccins utiles dans le traitement d'un cancer. L'invention concerne également des procédés servant à inhiber la croissance d'une tumeur chez un animal. L'invention concerne également des procédés servant à immuniser un animal contre un cancer, tel que le cancer de la prostate. Les adjuvants décrits sont constitués d'une matière de la matrice extracellulaire, telle qu'un tissu de sous-muqueuse de l'intestin grêle (SIS). Les préparations peuvent prendre la forme de feuilles, de gels, de liquides (injectables), de trocart ou d'une autre préparation solide ou semi-solide. L'invention permet l'inhibition accrue d'une tumeur d'un facteur supérieur ou égal à 2, par rapport à des préparations de vaccin sans la matière de matrice extracellulaire, ou d'un facteur de 4 à 5 par rapport à des préparations sans l'adjuvant promoteur de matières extracellulaires.

LandOfFree

Say what you really think

Search LandOfFree.com for Canadian inventors and patents. Rate them and share your experience with other people.

Rating

Extracellular matrix cancer vaccine adjuvant does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Extracellular matrix cancer vaccine adjuvant, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Extracellular matrix cancer vaccine adjuvant will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFCA-PAI-O-1550372

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.