Extracts and methods comprising curcuma species

A - Human Necessities – 61 – K

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A61K 36/906 (2006.01)

Patent

CA 2644093

The present invention relates to extracts of curcuma species plant material using supercritical CO2 extraction methods, methods of treating a subject suffering from suffering from amyloid plaque aggregation or fibril formation associated with, for example, Alzheimer's disease, and methods of inhibiting amyloid plaque aggregation or fibril formation in tissue thereof.

La présente invention concerne des extraits de matière végétale de l'espèce curcuma obtenus au moyen de procédés supercritiques d'extraction du CO2. L'invention concerne également des procédés de traitement d'un sujet souffrant d'une agrégation de la plaque amyloïde ou d'une formation de fibrilles associée à la maladie d'Alzheimer par exemple, et des procédés permettant l'inhibition de l'agrégation de la plaque amyloïde ou d'une formation de fibrilles dans les tissus dudit sujet.

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