Extracts of cucurbita sp., process for their preparation and...

B - Operations – Transporting – 01 – D

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B01D 11/02 (2006.01) A61K 8/92 (2006.01) A61K 8/97 (2006.01) A61K 31/56 (2006.01) A61Q 5/00 (2006.01) A61Q 19/00 (2006.01) A61K 35/78 (1990.01) A61K 7/48 (1990.01)

Patent

CA 2111036

A process for the preparation of novel extracts of Cucurbita pepo and cultivars thereof, the extracts obtainable thereby and their use in pharmacy and cosmetics are described. The said process comprises the following stages: a) the milling of the Cucurbita seeds, where appropriate b) the extraction of the milled Cucurbita seeds with supercritical carbon dioxide at a temperature from 34 to 50°C and under a pressure between 110 and 150 bar to remove unwanted products, c) the extraction of the active substances from the milled Cucurbita seeds with carbon dioxide under super-critical conditions or with organic solvents and d) the purification of the resulting extract by fractional countercurrent extraction with carbon dioxide under supercritical conditions. These extracts are used for the treatment of benign prostate hypertrophy and related clinical manifestations. The extracts are employed in cosmetics for the treatment of juvenile acne and as antiseborrhoea agents.

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