Eyedrops for promoting lacrimal secretion or treating...

A - Human Necessities – 61 – K

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A61K 38/02 (2006.01) A61K 38/22 (2006.01) A61P 27/02 (2006.01)

Patent

CA 2345414

Novel effects of natriuretic peptides in the field of ophthalmology. Lacrimal secretion promoters or eye drops for treating keratoconjunctival failure which contain as the active ingredient natriuretic peptides. The natriuretic peptides involve atrial natriuretic peptide (ANP), brain natriuretic peptide (BNP) and C natriuretic peptide (CNP). Typical examples of the keratoconjunctival failure include dry eye, corneal epithelial abrasion and corneal ulcer.

L'invention concerne les nouveaux effets de peptides natriurétiques dans le domaine de l'ophtalmologie, ainsi que des promoteurs de sécrétion lacrymale ou des gouttes ophtalmologiques permettant de traiter la kératoconjonctivite, ces promoteurs ou ces gouttes contenant lesdits peptides natriurétiques comme principes actifs. Ces peptides natriurétiques font intervenir un peptide natriurétique auriculaire (ANP), un peptide natriurétique cérébral (BNP), et un peptide natriurétique C (CNP). La kératoconjonctivite sèche, l'abrasion épithéliale de la cornée, et l'ulcération cornéenne sont certains exemples de kératoconjonctivite.

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