Ezetimibe compositions

Details Ezetimibe compositions Ezetimibe compositions

A - Human Necessities

61

K

A61K 9/14 (2006.01) A61K 31/397 (2006.01) A61K 31/70 (2006.01)

Patent

CA 2644905

Provided are ezetimibe compositions with improved solubility and increased bioavailability, methods of their preparation, and method of treatment using the same. An ezetimibe composition may be prepared, for example, by co-milling ezetimibe with at least one hydrophilic excipient.

La présente invention concerne des compositions à base d'ézétimibe de solubilité et de biodisponibilité améliorées, ainsi que des méthodes d'élaboration de telles compositions et une méthode de traitement utilisant lesdites compositions. Une composition d'ézétimibe peut être par exemple élaborée par co-broyage d'ézétimibe avec au moins un excipient hydrophile.

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