F1f0-atpase inhibitors and related methods

Details F1f0-atpase inhibitors and related methods F1f0-atpase inhibitors and related methods

C - Chemistry, Metallurgy

07

D

C07D 233/64 (2006.01) A61K 31/4164 (2006.01) A61K 31/4196 (2006.01) C07D 249/08 (2006.01) C12Q 1/42 (2006.01)

Patent

CA 2698248

The present invention relates to a family of guanidine-based F1F0-ATPase inhibitors, e.g., mitochondrial F1F0-ATPase inhibitors, methods for their discovery, and their use as therapeutic agents for treating certain disorders.

L'invention concerne une famille d'inhibiteurs de F1F0-ATPase à base de guanidine, par exemple des inhibiteurs de F1F0-ATPase mitochondriaux, des procédés pour leur découverte et leur utilisation en tant qu'agents thérapeutiques pour le traitement de certains troubles.

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