Fab i and inhibition of apicomplexan parasites

A - Human Necessities – 61 – K

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Details

A61K 38/00 (2006.01) A61K 31/09 (2006.01) A61K 38/44 (2006.01) C12N 9/02 (2006.01) C12N 15/10 (2006.01) G01N 33/50 (2006.01)

Patent

CA 2432992

Discovery and characterization of an apicomplexan Fab I gene and encoded enzyme and discovery of the triclosan as a lead compound, provide means to rationally design novel inhibitory compositions useful for prevention and treatment of apicomplexan related diseases.

L'invention concerne la découverte et la caractérisation d'un gène Fab I apicomplexan et une enzyme codée. L'invention traite également de la découverte du triclosan comme composé essentiel. Ces découvertes permettent de concevoir de manière rationnelle de nouvelles compositions inhibitrices pour prévenir et traiter les maladies liées aux apicomplexans.

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