C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 16/00 (2006.01) C07K 16/10 (2006.01) C12N 5/10 (2006.01)
Patent
CA 2527694
The present invention provides combinations of specific binding proteins, such as immunoglobulins, that are designed to be true combinations, essentially all components of the combination being functional and compatible with each other. The invention further provides a method for producing a composition comprising at least two different proteinaceous molecules comprising paired variable regions, said at least two proteinaceous molecules having different binding specificities, comprising contacting at least three different variable regions under conditions allowing for pairing of variable regions and harvesting essentially all proteinaceous molecules having binding specificities resulting from said pairing.
L'invention concerne des combinaisons pures de protéines de liaison spécifiques, telles que les immunoglobulines, dans lesquelles essentiellement tous les composants sont fonctionnels et mutuellement compatibles. Par ailleurs, l'invention concerne un procédé de production d'une composition qui contient au moins deux molécules protéiniques différentes possédant des régions variables appariées, ces molécules protéiniques ayant des spécificités de liaison différentes. Ce procédé consiste à mettre en contact au moins trois différentes régions variables dans des conditions qui favorisent l'appariement des régions variables et à collecter pratiquement l'ensemble des molécules protéiniques ayant des spécificités de liaison résultant dudit appariement.
Hoogenboom Hendricus Renerus Jacobus Mattheus
Logtenberg Ton
Borden Ladner Gervais Llp
Merus Biopharmaceuticals B.v.i.o.
LandOfFree
Fab library for the preparation of anti vegf and anti rabies... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Fab library for the preparation of anti vegf and anti rabies..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Fab library for the preparation of anti vegf and anti rabies... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1658733