Fabrication and packaging of suspended microchannel detectors

Details Fabrication and packaging of suspended microchannel detectors Fabrication and packaging of suspended microchannel detectors

C - Chemistry, Metallurgy

12

M

C12M 1/34 (2006.01) C12M 1/36 (2006.01) C12M 1/38 (2006.01) C12M 3/00 (2006.01) G01N 15/06 (2006.01) G01N 21/00 (2006.01) G01N 25/18 (2006.01) G01N 27/00 (2006.01) G01N 27/02 (2006.01) G01N 27/06 (2006.01) G01N 27/12 (2006.01) G01N 31/22 (2006.01) G01N 33/00 (2006.01)

Patent

CA 2540111

An apparatus for detecting an analyte in solution that has a suspended beam containing at least one microfluidic channel containing a capture ligand that bonds to or reacts with an analyte. The apparatus also includes at least one detector for measuring a change in the beam upon binding or reaction of the analyte. A method of making the suspended microfluidic channels is disclosed, as well as, a method of integrating the microfluidic device with conventional microfluidics having larger sample fluid channels.

L'invention concerne un appareil permettant de détecter un analyte dans une solution qui a un faisceau suspendu contenant au moins un canal microfluidique renfermant un ligand de capture qui se lie à un analyte ou qui réagit avec ce dernier. L'appareil comporte également au moins un détecteur pour mesurer un changement au niveau du faisceau lors de la liaison ou de la réaction de l'analyte. L'invention concerne en outre un procédé de fabrication de canaux microfluidiques suspendus, ainsi qu'un procédé d'intégration du dispositif microfluidique avec des structures microfluidiques classiques présentant des canaux fluidiques échantillons plus grands.

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