Facially amphiphilic polyaryl and polyarylalkynyl polymers...

C - Chemistry – Metallurgy – 07 – C

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C07C 211/00 (2006.01) A61K 31/135 (2006.01)

Patent

CA 2554163

The present invention discloses methods of use of facially amphiphilic polyaryl and polyarylalkynyl polymers and oligomers, including, but not limited to, pharmaceutical uses of the polymers and oligomers as antimicrobial agents and as antidotes for hemorrhagic complications associated with heparin therapy. The present invention also discloses novel facially amphiphilic polyaryl and polyarylalkynyl polymers and oligomers, compositions of the novel polymers and oligomers, including pharmaceutical compositions, and methods of designing and synthesizing the facially amphiphilic polyaryl and polyarylalkynyl polymers and oligomers.

La présente invention concerne des procédés d'utilisation de polymères et d'oligomères de polyaryle et de polyarylalkynyle amphiphiles au niveau facial, comprenant mais ne se limitant pas à des utilisations pharmaceutiques des polymères et des oligomères en tant qu'agents antimicrobiens et antidotes pour des complications hémorragiques, associées à une héparinothérapie. Cette invention a aussi pour objet de nouveaux polymères et oligomères de polyaryle et de polyarylalkynyle amphiphiles au niveau facial, des compositions des nouveaux polymères et oligomères, y compris des compositions pharmaceutiques, ainsi que des méthodes d'élaboration et de synthèse des polymères et des oligomères de polyaryle et de polyarylalkynyle amphiphiles au niveau facial.

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