Facially amphiphilic polymers and oligomers and uses thereof

C - Chemistry – Metallurgy – 07 – C

Patent

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Details

C07C 323/44 (2006.01) A61K 31/167 (2006.01) A61K 31/17 (2006.01) A61K 31/505 (2006.01) A61K 31/795 (2006.01) A61P 31/00 (2006.01) C07C 323/35 (2006.01) C07D 239/28 (2006.01)

Patent

CA 2519023

The present invention discloses methods of use of facially amphiphilic polymers and oligomers, including pharmaceutical uses of the polymers and oligomers as antimicrobial agents and antidotes for hemorrhagic complications associated with heparin therapy. The present invention also discloses novel facially amphiphilic polymers and oligomers and their compositions, including pharmaceutical compositions. The present invention further discloses the design and synthesis of facially amphiphilic polymers and oligomers.

La présente invention a trait à des procédés d'utilisation de polymères et d'oligomères à surface amphiphile, y compris des utilisations pharmaceutiques des polymères et oligomères en tant qu'agents antimicrobiens et antidotes contre des complications hémorragiques associées à la thérapie à l'héparine. La présente invention a également trait à de nouveaux polymères et oligomères à surface amphiphile et leurs compositions, comprenant des compositions pharmaceutiques. La présente invention a trait en outre à la conception et à la synthèse de polymères et d'oligomères à surface amphiphile.

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