A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 35/14 (2006.01) A61K 31/02 (2006.01) A61K 38/42 (2006.01) A61M 1/02 (2006.01)
Patent
CA 2117528
A method for facilitating autologous blood use by a patient facing a loss of blood, comprising the steps of removing and preferably storing a portion of the patient's blood, intravenously administering a biocompatible liquid in sufficient quantity to substantially maintain the patient's hemodynamic stability, wherein the liquid comprises an effective oxygen-delivery enhancing amount of a biocompatible synthetic oxygen carrier, after which the patient undergoes a loss of blood, and then readministering blood to the patient, preferably the stored blood. Also disclosed are use of biocompatible synthetic oxygen carriers in preparation of medicaments for use in the method, and compositions of such oxygen carriers for use in the method.
L'invention concerne un procédé destiné à faciliter l'utilisation de sang autologue par un patient subissant une perte de sang. Ledit procédé consiste à prélever et, de préférence, stocker une partie du sang du patient, à administrer par voie intraveineuse un liquide biocompatible en quantité suffisante pour maintenir la stabilité hémodynamique du patient, ledit liquide contenant un volume efficace augmentant l'apport d'oxygène de transporteur synthétique d'oxygène biocompatible, avant que le patient subisse une perte de sang. On réadministre ensuite le sang au patient, de préférence le sang stocké. Le mode d'utilisation de transporteurs synthétiques d'oxygène biocompatibles dans la préparation de médicaments utilisés dans ledit procédé ainsi que les compositions de ces transporteurs d'oxygène sont également décrits.
Faithfull Nicholas Simon
Keipert Peter E.
Reiss Jean G.
Roth Duane J.
Zuck Thomas F.
Alliance Pharmaceutical Corp.
Sim & Mcburney
LandOfFree
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