Facls as modifiers of the rb pathway and methods of use

Details Facls as modifiers of the rb pathway and methods of use Facls as modifiers of the rb pathway and methods of use

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01) A61K 31/7088 (2006.01) A61K 39/395 (2006.01) A61K 45/00 (2006.01) A61P 35/00 (2006.01) C12Q 1/00 (2006.01) C12Q 1/02 (2006.01) C12Q 1/25 (2006.01) G01N 33/573 (2006.01)

Patent

CA 2513615

Human FACL genes are identified as modulators of the RB pathway, and thus are therapeutic targets for disorders associated with defective RB function. Methods for identifying modulators of RB, comprising screening for agents that modulate the activity of FACL are provided.

Les gènes FACL humains sont identifiés comme des modulateurs de la voie RB et sont donc des cibles thérapeutiques pour des troubles associés à une défaillance de la fonction RB. Cette invention concerne des techniques d'identification des modulateurs de RB, comprenant la recherche d'agents qui modulent l'activité du gène FACL.

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