Factor h polymorphisms in the diagnosis and therapy of...

C - Chemistry – Metallurgy – 07 – K

Patent

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C07K 14/47 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2675618

The invention relates to antibodies, including monoclonal and polyclonal, or fragments thereof, which discriminate between the histidine and tyrosine isoforms of Complement Factor H and to their use in diagnostic methods and therapeutic treatments relating to Complement Factor H mediated diseases.

L'invention se rapporte à des anticorps, y compris des anticorps monoclonaux et polyclonaux ou des fragments de ces derniers, qui distinguent l'isoforme histidine de l'isoforme tyrosine du facteur H du complément, et à leur utilisation selon des procédés diagnostiques et dans des traitements thérapeutiques liés aux maladies médiées par le facteur H du complément.

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