Factor ixa specific antibodies displaying factor viiia like...

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 16/40 (2006.01) A61K 39/395 (2006.01) A61P 7/04 (2006.01) C07K 16/36 (2006.01) C12N 5/10 (2006.01) C12N 15/13 (2006.01)

Patent

CA 2538895

Ligands such as antibodies that can bind factor IX/factor IXa and increase the procoagulant activity of factor IXa (FIXa), pharmaceutical compositions containing such ligands, methods for treating patients afflicted with blood coagulation with such ligands, and a nucleic acid that encodes, or a cell that expresses such ligands, are provided.

La présente invention a trait à des ligands tels que des anticorps capables d'effectuer une liaison facteur IX/facteur IXa et accroître l'activité procoagulante du facteur XIa (FIXa), à des compositions pharmaceutiques contenant de tels ligands, à des procédés de traitement de patients souffrant de coagulation sanguine avec de tels ligands, et un acide nucléique codant pour, ou un cellule exprimant de tels ligands.

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