Factor x analog with an improved ability to be activated

Details Factor x analog with an improved ability to be activated Factor x analog with an improved ability to be activated

C - Chemistry, Metallurgy

07

K

C07K 14/00 (2006.01) C12N 9/64 (2006.01)

Patent

CA 2380844

This invention describes a factor Xa analog which has a substitution of a minimum of one of the amino acid between Glu226 and Arg234 and possibly Ile235, relative to the amino acid numbering according to Figure 1, a preparation containing the activated form of the factor X analog, and a method for the production of these molecules.

La présente invention concerne un analogue de facteur Xa, dont au moins un acide aminé est substitué entre les positions Glu226 et Arg234 et éventuellement Ile235, par référence à la numérotation indiquée sur la Figure 1. Elle concerne aussi une préparation contenant la forme activée de l'analogue de facteur X, ainsi qu'un procédé de production des ces molécules.

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