Factor x deletion mutants and analogues thereof

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/57 (2006.01) A61K 38/48 (2006.01) C12N 9/64 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2282728

The invention relates to factor X.DELTA. analogues, comprising a deletion of the amino acids Arg180 to Arg234 and a modification in the region of the amino acid sequence between Gly173 and Arg179. The invention also relates to preparations containing said factor X.DELTA. analogues and methods for the production thereof.

Analogues de facteur X.DELTA. présentant une délétion des acides aminés Arg180 à Arg234, ainsi qu'une modification dans le domaine de la séquence d'acides aminés située entre Gly173 et Arg179, préparations contenant ces analogues et procédé de production desdits analogues.

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