C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 409/14 (2006.01)
Patent
CA 2674924
The present invention is directed to compounds represented by Formula (I) or a pharmaceutically acceptable salt, ester, or prodrug thereof which are inhibitors of Factor Xa. The present invention is also directed to intermediates used in making such compounds, pharmaceutical compositions containing such compounds, methods to prevent or treat certain conditions characterized by undesired thrombosis and methods of inhibiting the coagulation of a blood sample.
L'invention concerne des composés représentés par la formule (I) ou un sel, un ester ou un promédicament pharmaceutiquement acceptable de ceux-ci qui sont des inhibiteurs du facteur XA. La présente invention concerne également des intermédiaires utilisés dans la fabrication de tels composés, des compositions pharmaceutiques contenant de tels composés, des procédés pour empêcher ou traiter certaines affections caractérisées par une thrombose non souhaitée et des procédés d'inhibition de la coagulation d'un échantillon de sang.
Jia Zhaozhong J.
Pandey Anjali
Scarborough Robert
Song Yonghong
Millennium Pharmaceuticals Inc.
Torys Llp
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