C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 207/09 (2006.01) A61K 31/4025 (2006.01) C07D 207/10 (2006.01)
Patent
CA 2565437
The present invention is directed to compounds represented by Formula I and pharmaceutically acceptable salts, solvates, hydrates, and prodrugs thereof which are inhibitors of Factor Xa. The present invention is also directed to and intermediates used in making such compounds, pharmaceutical compositions containing such compounds, methods to prevent or treat a number of conditions characterized by undesired thrombosis and methods of inhibiting the coagulation of a blood sample.
L'invention concerne des composés de formule (I) et des sels, des solvates, des hydrates, et des promédicaments pharmaceutiquement acceptables de ceux-ci. Ces composés sont des inhibiteurs du facteur Xa. L'invention concerne des intermédiaires utilisés pour fabriquer de tels composés, des compositions pharmaceutiques contenant de tels composés, des méthodes pour prévenir ou pour traiter un certain nombre de troubles caractérisés par une thrombose indésirable, et des méthodes d'inhibition de la coagulation d'un échantillon sanguin.
Bauer Shawn M.
Jia Zhaozhong J.
Probst Gary D.
Scarborough Robert M.
Zhang Yanchen
Millennium Pharmaceuticals Inc.
Torys Llp
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