A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/04 (2006.01) G01N 33/68 (2006.01)
Patent
CA 2190296
Factors and methods for disrupting or inhibiting the association of protomers of a multimeric protein are described. Such inhibition reduces the biological activity of the target protein, which is desirable in the case of certain physiological disorders. Methods of screening candidate factors that mimic the interface between protomers of a multimeric protein, so as to identify a factor that disrupts or inhibits association of the protomers, are also described. In particular, peptides that inhibit the association of protomers of a growth factor having a cysteine knot, such as a neurotrophin, aredescribed.
Dory Magdalena I.
Riopelle Richard John
Ross Gregory M.
Shamovsky Igor L.
Weaver Donald F.
Queen's University At Kingston
Steeg Carol Miernicki
LandOfFree
Factors and methods for reducing biological activity of a... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Factors and methods for reducing biological activity of a..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Factors and methods for reducing biological activity of a... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1388499