Farnesyl-protein transferase inhibitors

Details Farnesyl-protein transferase inhibitors Farnesyl-protein transferase inhibitors

C - Chemistry, Metallurgy

07

D

C07D 307/93 (2006.01) A61K 31/34 (2006.01) A61K 31/66 (2006.01) C07C 53/136 (2006.01) C07D 303/38 (2006.01) C07D 307/935 (2006.01)

Patent

CA 2321719

Substantially pure preparations of phosphosesquiterpenes are described. The compounds inhibit farnesyl-protein transferase activity and are useful for the treatment of cancer. Methods for inhibiting farnesyl-protein transferase activity are also described.

L'invention concerne des préparations pratiquement pures de phosphosesquiterpènes. Ces composés inhibent l'activité de la farnesyl protéine transférase et sont utiles pour le traitement du cancer. Elle concerne également des procédés servant à inhiber l'activité de farnesyl protéine transférase.

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