Farnesyl protein transferase inhibitors with in vivo...

A - Human Necessities – 61 – K

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A61K 41/00 (2006.01) A61K 31/47 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2336624

The present invention is concerned with the finding that farnesyl protein transferase inhibitors have radiosensitizing properties which makes them useful for preparing a pharmaceutical composition for administration before, during or after irradiation of a tumor for treating cancer in vivo.

L'invention concerne l'utilisation d'inhibiteurs de farnésyl protéine transférase, dont on a constaté qu'ils avaient des propriétés de radiosensibilisation utiles pour l'élaboration d'une composition pharmaceutique destinée à être administrée avant, pendant ou après l'irradiation d'une tumeur dans le cadre du traitement d'un cancer in vivo.

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