Farnesyl transferase inhibiting 1,2-annelated quinoline...

Details Farnesyl transferase inhibiting 1,2-annelated quinoline... Farnesyl transferase inhibiting 1,2-annelated quinoline...

C - Chemistry, Metallurgy

07

D

C07D 487/04 (2006.01) A61K 31/519 (2006.01)

Patent

CA 2410232

The invention relates to (-)-5-(3-Chlorophenyl)-.alpha.-(4-chlorophenyl)- .alpha.-(1-methyl-1H-imidazol-5-yl)tetrazolo-[1,5-a]quinazoline-7-methanamine and its pharmaceutically acceptable acid addition salts, and the use of such compounds in medicine especially for the treatment of cancer.

L'invention concerne une (-)-5-(3-Chlorophényl)-.alpha.-(4-chlorophényl)-.alpha.-(1-méthyl-1<i>H</i>-imidazol-5-yl)tétrazolo-[1,5-a]quinazoline-7-méthanamine et ses sels d'addition d'acide pharmaceutiquement acceptables. L'invention traite également de l'utilisation de ces composés en médecine particulièrement pour le traitement du cancer.

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