Farnesyl transferase inhibiting tricyclic quinazoline...

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 487/04 (2006.01) A61K 31/519 (2006.01) A61P 35/00 (2006.01) C07D 257/00 (2006.01)

Patent

CA 2481480

This invention comprises the novel compounds of formula (I) wherein r, s, t, R1, R2, R3, R4, R5, and R6 have defined meanings, having farnesyl transferase inhibiting activity; their preparation, compositions containing them and their use as a medicine.

La présente invention concerne de nouveaux composés de formule (I), dans laquelle r, s, t, R¿1?, R¿2?, R¿3?, R¿4?, R¿5?, et R¿6? ont des significations définies, qui présentent une activité d'inhibition de farnésyl transférase, leur préparation, des compositions les contenant et leur utilisation en tant que médicament.

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