Fast acting and persistent topical antiseptic

Details Fast acting and persistent topical antiseptic Fast acting and persistent topical antiseptic

A - Human Necessities

01

N

A01N 25/02 (2006.01) A01N 31/02 (2006.01) A01N 37/02 (2006.01) A01N 37/06 (2006.01) A01N 43/16 (2006.01) A01N 55/02 (2006.01) A01N 57/12 (2006.01) A01N 61/00 (2006.01) A61K 31/44 (2006.01)

Patent

CA 2217032

Stable antiseptic compositions having both a quick-kill of microorganisms with a substantial reduction in number, and a profound persistent effect over a broad spectrum of microorganisms, including but not limited to bacteria, yeasts, molds, and viruses, without significant irritation of the tissue to which they are applied are disclosed. The quick-kill component of the present invention comprises one or more alcohols, lipids, preservatives or microbicidal nitrogen containing compounds. The persistent component of the present invention comprises one or more lipids, preservatives, or microbicidal nitrogen containing compounds which preferably bind to either or both of the skin surface and intracellular structures within the epidermis. Additional components include antioxidants, ethoxylated cetyl and stearyl alcohols, coloring and texturing compounds. Preferred solutions comprise an alcohol such as 70 % n-propanol or ethanol and bispyrithiones and further include fatty acids and fatty acid esters.

L'invention se rapporte à des compositions antiseptiques stables, ayant un pouvoir d'élimination rapide et important en nombre sur des micro-organismes, ainsi qu'un profond effet rémanent sur un large spectre de ces micro-organismes, notamment, mais pas exclusivement, des bactéries, des levures, des moisissures et des virus, mais n'irritant que très sensiblement le tissu sur lequel elles sont appliquées. Le composant à pouvoir d'élimination rapide comprend un ou plusieurs alcools, lipides, conservateurs ou composés microbicides renfermant de l'azote. Le composant à effet rémanent comprend un ou plusieurs lipides, conservateurs ou composés microbicides renfermant de l'azote qui, de préférence, se lient entre eux ou à la surface de la peau et aux structures intracellulaires de l'épiderme. Des composants additionnels comprennent des antioxydants, des alcools cétyliques et stéariques éthoxylés et des composés de coloration et de modification de texture. Des solutions préférées comprennent un alcool tel que l'alcool n-propylique ou l'alcool éthylique dans une teneur de 70 % et des bispyrithiones, ainsi que des acides gras et des esters d'acides gras.

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