Fast assignment of adequate neoadjuvant chemotherapy for...

C - Chemistry – Metallurgy – 12 – Q

Patent

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C12Q 1/68 (2006.01)

Patent

CA 2650448

Subject of invention allow to synthesize DNA and identification of germline BRCAl genetic abnormalities which are correlated with a significantly decreased clinical response to neoadjuvant chemotherapy based on taxane-derived cytostatics in breast cancer patients.

La présente invention concerne la synthèse de l'ADN et l'identification dans la lignée germinale d'anomalies génétiques du gène BRCAl corrélées à une diminution importante de la réponse clinique à une chimiothérapie préopératoire basée sur des cytostatiques dérivés de taxane chez des patientes ayant un cancer du sein.

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