Fast dissolving dosage forms having reduced friability

Details Fast dissolving dosage forms having reduced friability Fast dissolving dosage forms having reduced friability

A - Human Necessities

61

K

A61K 9/20 (2006.01) A61K 9/00 (2006.01)

Patent

CA 2479735

Disclosed is a rapidly disintegrating or dissolving (fast melt) solid dosage form of at least one active agent and at least one pharmaceutically acceptable water-disintegrable or water-soluble excipient, wherein the dosage form has two opposed double-convex surfaces. The dosage form of the invention has the advantage of exhibiting low friability with a very low disintegration time.

L'invention concerne une forme posologique solide à désintégration ou dissolution rapide (fusion rapide) comprenant au moins un agent actif et au moins un excipient pharmaceutiquement acceptable désintégrable dans l'eau ou soluble dans l'eau, cette forme posologique comportant deux surfaces biconvexes opposées. La forme posologique de l'invention se caractérise en ce qu'elle présente une friabilité réduite et une durée de désintégration très courte.

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