Fast-dissolving galanthamine hydrobromide tablet

Details Fast-dissolving galanthamine hydrobromide tablet Fast-dissolving galanthamine hydrobromide tablet

A - Human Necessities

61

K

A61K 31/55 (2006.01) A61K 9/20 (2006.01)

Patent

CA 2180703

The present invention is concerned with a fast-dissolving tablet for oral administration comprising as an active ingredient a therapeutically effective amount of galanthamine hydrobromide (1:1) and a pharmaceutically acceptable carrier, characterized in that said carrier comprises a spray-dried mixture of lactose monohydrate and micro-crystalline cellulose (75: 25) as a diluent, and a disintegrant; and with a direct compression process of preparing such fast-dissolving tablets.

Comprimé à dissolution rapide pour administration orale avec, comme ingrédient actif, une quantité thérapeutique de bromhydrate de galanthamine (1/1) et un véhicule acceptable en pharmacie, ce dernier renfermant, comme diluant, un mélange de lactose monohydraté et de cellulose micro-cristallisée (75/25), séché par pulvérisation, et un désintégrant; procédé pour l'obtention directe par compression de ces comprimés à dissolution rapide.

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