A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/20 (2006.01) A61K 9/00 (2006.01) A61K 9/51 (2006.01) A61K 31/496 (2006.01)
Patent
CA 2436287
The present invention relates to processes for the preparation of tablets which dissolve rapidly in the mouth and provide an excellent mouth feel. The tablets of the invention comprise a compound which melts at about 37 ~C or lower, have a low hardness, high stability and generally comprise few insoluble disintegrants which may cause a gritty or chalky sensation in the mouth. Convenient and economically feasible processes by which the tablets of the invention may be produced are also provided.
L'invention concerne des procédés de préparation de comprimés qui se dissolvent rapidement dans la bouche et provoquent une bonne sensation buccale. Ces comprimés comprennent un composé qui fond à 37 ·C environ, ou à une température inférieure, possèdent une faible dureté, une stabilité élevée et contiennent généralement peu d'agents délitants insolubles qui pourraient provoquer une sensation de craie ou gréseuse dans la bouche. L'invention concerne aussi des procédés commodes et économiques au moyen desquels il est possible de produire les comprimés de l'invention.
Abu-Izza Khawla A.
Li Vincent H.
Look Jee L.
Parr Graham D.
Schineller Matthew K.
Robic
Wyeth
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