G - Physics – 01 – N
Patent
G - Physics
01
N
G01N 27/27 (2006.01)
Patent
CA 2564511
A system for carrying out fast perfusion for the patch clamp techniques useful in studying the effect of compounds on ion transfer channels in biological tissue is disclosed. The invention additionally includes microperfusion chamber assemblies capable of utilizing small amounts of material to be tested and small amounts of liquid carrier, thereby enabling multiple tests to be completed in a short period of time. The invention more broadly relates to an electrophysiology drug handling and application set up for screening chemicals such as drugs while providing high throughput and low volumes of solutions and samples.
L'invention concerne un système permettant d'effectuer une perfusion rapide destiné à des techniques patch clamp utilisées pour étudier l'effet de composés sur des canaux de transfert ionique dans un tissu biologique. L'invention concerne également des ensembles de chambres de microperfusion capables d'utiliser de petites quantités de matériau à soumettre à un essai et de petites quantités de milieu liquide, ce qui permet d'effectuer des essais multiples pendant une courte période. L'invention concerne plus largement la manipulation d'un médicament électrophysiologique et une application établie afin de cribler des substances chimiques, telles que des médicaments, tout en fournissant un débit élevé et de faibles volumes de solutions et d'échantillons.
Bowlby Mark Robert
Vasylyev Dmytro Vasylyovych
Torys Llp
Wyeth
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