Fast release composition including melt granules of a...

Details Fast release composition including melt granules of a... Fast release composition including melt granules of a...

A - Human Necessities

61

K

A61K 9/16 (2006.01) A61K 9/20 (2006.01)

Patent

CA 2575499

Solid oral dosage forms that include melt granules of a moisture-sensitive therapeutic compound and a hydrophobic melt component. The melt granules better protect the therapeutic compound from hydrolytic degradation. Such solid oral dosage forms also possess immediate-release characteristics rather than that associated with extended-release or controlled-release drug products.

L'invention concerne des formes solides pour dosage par voie orale, comprenant des granulés fondus d'un composé thérapeutique sensible à l'humidité et un constituant fondu hydrophobe. Les granulés fondus protègent mieux le composé thérapeutique de la décomposition hydrolytique. Les formes solides pour dosage par voie orale présentent également des caractéristiques de libération immédiate, plutôt que celles associées aux produits pharmaceutiques à libération prolongée ou à libération contrôlée.

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