Fat-binding polymers

C - Chemistry – Metallurgy – 08 – F

Patent

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Details

C08F 34/00 (2006.01) A61K 31/785 (2006.01) A61K 31/787 (2006.01) A61P 3/04 (2006.01) C08F 16/36 (2006.01) C08F 20/58 (2006.01) C08F 26/02 (2006.01)

Patent

CA 2490219

The present invention provides fat-binding polymers, which comprise dialkanolamine, dialkanolammonium, aminoalkylpolyol, and ammoniumalkylpolyol pendant groups for subjects in need of fat removal from the gastrointestinal tract, particularly subjects suffering from steatorrhea and/or experiencing side effects from lipase inhibitors. Patients being administered with lipase inhibitors are typically being treated for Type II Diabetes, streatorrhea, and hypertriglyceridemia. The fat binding polymers of this invention are also suitable for use with obese subjects.

L'invention concerne des polymères liant des graisses, comportant des groupes latéraux dialcanolamine, dialcanolammonium, aminoalkylpolyol, et ammoniumalkylpolyol, destinés à des sujets nécessitant une élimination de graisse dans le tractus gastro-intestinal, en particulier destinés à des sujets souffrant de stéatorrhée et/ou connaissant des effets secondaires provenant d'inhibiteurs de lipase. Les patients qui reçoivent des inhibiteurs de lipase sont classiquement traités pour des diabètes de type II, la stéatorrhée, et l'hypertriglycéridémie. Les polymères liant des graisses de cette invention peuvent aussi être utilisés avec des sujets obèses.

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