Fatty acid elongases

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/54 (2006.01) A01H 5/00 (2006.01) C12N 9/10 (2006.01) C12N 15/29 (2006.01) C12N 15/82 (2006.01)

Patent

CA 2292770

Nucleic acids are disclosed that encode fatty acid .beta.-keto acyl synthases from plants. Such synthases are effective for producig very long chain fatty acids (VLCFA), e.g., C22 to C26, preferentially saturated but also monounsaturated. Also disclosed are polypeptides encoded by such nucleic acids. Transgenic plants expressing these polypeptides exhibit altered levels of VLCFA in one or more tissues, such as seeds or leaves.

On décrit des acides nucléiques qui codent des .beta.céto acyle synthases d'acide gras issues de plantes. Ces synthases sont efficaces pour produire des acides gras à très longue chaîne (AGTLC), par exemple des acides gras C22 à C26 qui sont de préférence saturés mais qui peuvent également être mono-insaturés. On décrit également des polypeptides codés par ces acides nucléiques. Des plantes transgéniques exprimant ces polypeptides présentent des niveaux modifiés de AGTLC dans un ou plusieurs tissus, tels que les graines ou les feuilles.

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