Fatty acid esters as bioactive compounds

C - Chemistry – Metallurgy – 07 – C

Patent

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Details

C07C 69/587 (2006.01) A61K 31/23 (2006.01) A61K 31/385 (2006.01) A61K 31/405 (2006.01) A61K 47/48 (2006.01) C07C 69/007 (2006.01) C07C 69/76 (2006.01) C07C 69/767 (2006.01) C07D 209/28 (2006.01) C07D 213/30 (2006.01) C07D 213/66 (2006.01) C07D 233/94 (2006.01) C07D 279/36 (2006.01) C07D 321/00 (2006.01) C07D 339/04 (2006.01) C07D 499/00 (2006.01) C07F 9/09 (2006.01) C07F 9/655 (2006.01) C07J 1/00 (2006.01) C07J 5/00 (2006.01)

Patent

CA 2218702

Compounds of structure (1), and when for use in therapy: where R1 is an acyl group derived from a C16-3o fatty acid with two or more cis or trans double bonds and particularly an n-6 or n-3 series EFA or conjugated linoleic acid, or columbinic acid, or parinaric acid and R2 is as Ri the same or different, or any other nutrient, drug or other bioactive residue released as the active in the body and R3 is either hydrogen, fully hydrocarbon, or containing heteroatoms, preferably an alkyl group particularly a C1-C4 alkyl group.

Cette invention concerne des composés représentés par la formule (I) ainsi que les cas d'utilisation de ces composés en thérapie. Dans la formule (I), R1 représente un groupe acyle dérivé d'un acide gras C16-30 comportant au moins deux liaisons doubles cis ou trans et en particulier un acide gras essentiel des séries n-6 et n-3 ou un acide linoléique conjugué, l'acide de niobium, ou l'acide parinarique et R2 est comme R1, identique ou différent, ou tout autre agent nutritif, médicament ou autre résidu bioactif libéré en tant qu'agent actif à l'intérieur du corps et R3 est soit l'hydrogène, soit entièrement hydrocarbure, ou contenant des hétéroatomes, soit un groupe alkyle et en particulier un groupe alkyle C1-C4.

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