A - Human Necessities – 23 – D
Patent
A - Human Necessities
23
D
A23D 9/00 (2006.01) A61L 27/30 (2006.01) A61L 29/08 (2006.01) A61L 31/08 (2006.01) C11C 3/10 (2006.01)
Patent
CA 2652314
The invention relates to a mixture (a) of fatty acid triglycerides having a slip melting point above 500C, the fatty acid composition of said mixture (a) comprising at least two different fatty acids and comprising from 20 to 95% by weight of saturated fatty acids and 80 to 5% by weight of unsaturated fatty acids, and wherein at least one fatty acid triglyceride (a1 ) from said mixture (a) bears the same saturated fatty acid residue on each position of the glycerol moiety and corresponds to at least 10% by weight of said mixture (a). This mixture is useful in the coating of medical devices to improve bio-compatibility, stability, and drug release.
L'invention concerne un mélange (a) de triglycérides d'acides gras ayant un point de fusion par glissement dans un capillaire (<= slip melting point >=) supérieur à 500 °C, ledit mélange (a) étantcomposé d'au moins deux acides gras différents et comprenant de 20 à 95 % en poids d'acides gras saturés et de 80 à 5 % en poids d'acides gras insaturés. Au moins un triglycéride (a1) d'acides gras du mélange (a) porte le même résidu d'acide gras saturé sur chaque position du fragment glycérol et représente au moins 10 % en poids du mélange (a). Le mélange de l'invention s'avère utile pour enrober des dispositifs médicaux dans le but d'améliorer leur biocompatibilité, leur stabilité et la libération des médicaments.
de Scheerder Ivan
Jacobs Pierre
Sels Bert
Smart & Biggar
Ziscoat Nv
LandOfFree
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