Fc receptor binding proteins

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 16/28 (2006.01) A61P 37/00 (2006.01)

Patent

CA 2722082

This disclosure provides, inter alia, proteins that bind to FcRn, e.g., immunoglobulins that inhibit FcRn with high affinity and selectivity. The FcRn-binding proteins can be used to treat a variety of disorders including autoimmune disorders.

La présente invention concerne, entre autres, des protéines qui se lient au récepteur Fc néonatal, par exemple, des immunoglobulines qui inhibent le récepteur Fc néonatal avec une affinité et une sélectivité élevées. Les protéines de liaison au récepteur Fc néonatal peuvent être utilisées pour traiter une variété daffections comprenant les affections auto-immunes.

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