Fcrn antibodies and uses thereof

Details Fcrn antibodies and uses thereof Fcrn antibodies and uses thereof

C - Chemistry, Metallurgy

12

N

C12N 15/13 (2006.01) A61K 38/19 (2006.01) A61K 39/395 (2006.01) A61K 51/08 (2006.01) A61K 51/10 (2006.01) A61P 37/02 (2006.01) C07K 16/46 (2006.01) C12N 5/16 (2006.01) C12P 21/08 (2006.01) C12Q 1/00 (2006.01) G01N 33/566 (2006.01)

Patent

CA 2606378

In certain embodiments, this present invention provides polypeptide compositions (e.g., antibodies and antigen binding portions thereof that bind to FcRn), and methods for modulating FcRn activity. In other embodiments, the present invention provides methods and compositions for treating autoimmune disorders.

Dans certains modes de réalisation, l'invention concerne des compositions de polypeptides (par ex. des anticorps et des parties de liaison d'antigènes de ces anticorps se liant à FcRn), ainsi que des procédés de modulation de l'activité de FcRn. Dans d'autres modes de réalisation, l'invention concerne des procédés et des compositions de traitement de maladies auto-immunes.

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