Feline calicivirus genes and vaccines, in particular...

Details Feline calicivirus genes and vaccines, in particular... Feline calicivirus genes and vaccines, in particular...

C - Chemistry, Metallurgy

12

N

C12N 15/86 (2006.01) A61K 39/295 (2006.01) C07K 14/08 (2006.01) C07K 14/535 (2006.01) C07K 14/74 (2006.01) A61K 39/00 (2006.01) A61K 48/00 (2006.01)

Patent

CA 2379539

The invention relates to the sequence of the capsid gene and a corresponding cDNA sequence, of a dominant FCV strain called FCV 431. It also relates to the sequence of the capsid gene as well as the cDNA sequence of a complementary strain called G1. The cDNA sequences may be incorporated into expression vectors for the preparation of immunogenic preparations and of recombinant or subunit vaccines allowing vaccination against feline calicivirosis.

L'invention concerne la séquence du gène de capside et une séquence d'ADNc correspondante, d'une souche FCV dominante dénommée FCV 431. Elle concerne aussi la séquence du gène de capside ainsi que la séquence d'ADNc d'une souche complémentaire dénommée G1. Les séquences d'ADNc peuvent être incorporées dans des vecteurs d'expression en vue de la préparation de préparations immunogènes et de vaccins recombinés ou sous-unitaires permettant la vaccination contre la calicivirose féline.

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