Feline leukemia virus vaccine

Details Feline leukemia virus vaccine Feline leukemia virus vaccine

C - Chemistry, Metallurgy

12

N

530/15, 530/7.08

C12N 15/48 (2006.01) C07K 7/08 (2006.01) C07K 14/15 (2006.01) C12N 1/20 (2006.01) C12P 21/00 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1334387

Polypeptides that are synthesized or expressed directly in microorganisms, include an amino acid sequence that is homologous to at least a portion of gp70 envelope protein of FELV, and are immunogens that elicit or prime a humoral response in cats and immunize cats against FeLV infection. The microbially produced polypeptides are exemplified by a group of E. coli-expressed fusion proteins that comprise a portion of the trp leader peptide and a portion of the trp E protein fused to various portions of a subgroup B gp70 envelope protein. The synthesized polypeptides are exemplified by polypeptides that are homologous to segments of the hydrophilic domains of the gp70 protein.

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